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Epidemiologic studies highlight soy’s potential associations with prevention of cancer, CVD, and diabetes

March 1, 2023 by Dr. Mark Messina

Epidemiologic studies are not designed to establish cause and effect relationships because it is not possible to control for all potentially confounding variables. Additionally, it is difficult to accurately assess dietary intake. Nevertheless, epidemiologic studies have played an important role in informing dietary guidelines. Although intervention studies carry the most weight within the scientific community, […]

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Can Childhood Soy Consumption Decrease Risk of Breast Cancer?

June 1, 2022 by Dr. Mark Messina

In 1995, Lamartiniere et al.1,2 proposed that the isoflavone genistein when consumed early in life reduces risk of developing breast cancer later in life. Over the past nearly 30 years, both animal3 and epidemiologic evidence4-7 has accumulated in support of this proposal. Nevertheless, the hypothesis that consuming isoflavone-rich soy during childhood and/or adolescence reduces breast […]

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Genistein may be useful for the treatment of triple-negative breast cancer

January 12, 2022 by Dr. Mark Messina

Modern research interest in soyfoods began with a focus on cancer prevention and treatment.1 Much of this interest can be attributed to the soybean being a uniquely rich source of isoflavones, and in particular, genistein. New pre-clinical research by Sharma et al.2 suggests that genistein may have a role in the prevention and treatment of […]

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Systematic Review Supports the Safety of Soy for Women with Breast Cancer

August 17, 2021 by Dr. Mark Messina

Beginning in the late 1990s, concerns arose that soy increases breast cancer risk and worsens the prognosis of women with this disease despite the historically low breast cancer incidence rates in soyfood-consuming countries.1 However, observational data published beginning in 2009,2 showed just the opposite, post-diagnosis soy intake was associated with reduced mortality and recurrence.3 A […]

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Glyphosate declared non-carcinogenic in draft European report, and by agencies worldwide

July 14, 2021 by Dr. Mark Messina

The European Union’s Assessment Group on Glyphosate (AGG) recently released an 11,000-page draft report concluding that glyphosate, the world’s most widely used herbicide, does not warrant being declared carcinogenic (see exact wording below).1 If adopted by the AGG, it will add to the long list of health agencies that have declared the world’s most widely […]

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Is Soy Infant Formula Use Protective Against Breast Cancer?

August 27, 2020 by Dr. Mark Messina

The historically low incidence rates of breast cancer in soyfood-consuming countries led to initial enthusiasm that soy intake could reduce risk of developing this disease. While appropriate as a basis for speculation, considerably more informative are breast cancer rates among Asian women who regularly consume soy in comparison to those who do not.  Such comparisons […]

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Soymilk and Cow’s Milk: New Evidence to Consider

May 20, 2020 by Dr. Mark Messina

The health effects of cow’s milk have been hotly debated over the past couple of decades. Two recent publications call into question current dietary milk recommendations,1,2 one of which also highlights the benefits of replacing cow’s milk with soymilk in relation to breast cancer risk.2 In a review on milk and health published in the […]

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Understanding How Soy Affects Breast Cancer Risk

February 27, 2020 by Dr. Mark Messina

Excitement about the possibility that soyfoods reduce risk of developing breast cancer began in earnest 30 years ago. While over this time support for a protective effect has waxed and waned, there has been a constant struggle to identify a mechanism by which soy could exert its proposed protective effect. It isn’t necessary to know […]

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Cervical Cancer

December 20, 2019 by Dr. Mark Messina

Expert notes soy doesn’t increase risk of cervical cancer but fails to highlight that it may be proactive against this disease. A woman who frequently consumed soy was diagnosed with cervical cancer. Upon hearing the news, the woman’s mother said she knew the reason. “All the soy” in her diet “was the leading cause of […]

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Skeletal Benefits of Soy

June 18, 2019 by Dr. Mark Messina

There may be two important reasons for women with breast cancer to consume soy. The skeletal benefits of soy have been investigated in earnest for 30 years. Attention focused first on the possible advantages of soy protein over animal protein1,2 and, second, on the estrogen-like effects of isoflavones.3 Recently reported 10-year follow up data from […]

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