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Isoflavones associated with lower fracture risk in Chinese men

October 21, 2021 by Dr. Mark Messina

The first of its kind research from Shanghai indicates isoflavones may reduce risk of fractures in men.1 Even a superficial examination of the literature quickly reveals that most of the soy research focused on bone health involves women. For example, all five of the clinical trials examining bone mineral density (BMD) that were at least […]

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Origins of the Soy Feminization Myth

August 20, 2021 by Dr. Mark Messina

There are likely some folks, including health professionals, who are still uncertain about whether soy feminizes men. This uncertainty is understandable given that even today, claims that soy feminizes men can still be found. These claims exist despite definitive data showing neither soy nor soy isoflavones lower testosterone levels,1 raise estrogen levels,1 affect sperm or […]

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Soymilk and Kidney Stones

June 23, 2021 by Dr. Mark Messina

Nephrolithiasis, or kidney stones, is the presence of renal calculi caused by a disruption in the balance between solubility and precipitation of salts in the urinary tract and in the kidneys.  Approximately 10% of people participating in the 2013–2014 National Health and Nutrition Examination reported having kidney stones. The highest prevalence was observed in males […]

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No Hormonal Effects Observed in Infants on Soy Formula

June 4, 2021 by Dr. Mark Messina

This blog rarely discusses research on soy infant formula (SIF). There are many reasons for not doing so. For example, on a body weight basis, isoflavone exposure is much higher in infants fed SIF than in children or adults consuming soyfoods in amounts compatible with Japanese consumption.1,2 Also, during the first few weeks and months […]

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Soy Protein Promotes Men’s Health, Muscle Mass, and Strength

April 29, 2021 by Dr. Mark Messina

A recent surge in evidence from an array of sources highlights the nutritional and health attributes of soy protein for men. These sources include newly published research, the recently released 2020-2025 Dietary Guidelines for Americans and an authorized FDA health claim. Nutrition scientists increasingly recognize the importance of maintaining muscle mass and strength throughout life. […]

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Supplementing Plant-Based Diets with Soy Protein Increases Muscle Mass and Strength

February 25, 2021 by Dr. Mark Messina

Considerable work has been devoted to determining the optimal protein for building muscle mass and strength in response to resistance exercise training (RET). Until recently, there was a consensus within the scientific community that whey protein performed better than other proteins in this regard.1 However, studies published over the past couple of years showed that […]

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Many Soyfoods Suitable for Low Tyramine Diets

February 19, 2021 by Dr. Mark Messina

Monoamine oxidase inhibitors (MAOIs) were first introduced in the 1950s to treat depression.1,2 They are a separate class from other antidepressants, treating different forms of depression as well as other nervous system disorders.3 However, relatively soon after their introduction, MAOIs were quickly associated with a potentially fatal interaction with foods containing tyramine. Why is the […]

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Soy Protein Does Not Lower Testosterone or Raise IGF-1 Levels in Men

January 31, 2021 by Dr. Mark Messina

Research from the University of Illinois by Bosland et al.1 provides important insight about the effects of soy protein on hormone levels in men. This study is especially notable because of its size and duration. The results show that soy protein affects neither circulating levels of free testosterone (biologically active form) or insulin-like growth factor-1 […]

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Plant-based Diets and Fracture Risk

December 17, 2020 by Dr. Mark Messina

Recent research raises concerns that plant-based, and especially vegan diets, increase fracture risk.1 If indeed this is the case, consuming soyfoods might help offset any potential vulnerability. The main research in question is the EPIC-Oxford study in the U.K. which involves approximately 55,000 (mostly white) participants, about 2,000 of whom are vegans (this cohort oversampled […]

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New Insights about Dietary Protein Requirements

December 2, 2020 by Dr. Mark Messina

Evidence suggests consuming protein in excess of the recommended dietary allowance (RDA) can increase lean body mass. Evidence also indicates that high-quality plant protein, such as soy protein, can increase lean body mass as effectively as animal protein. A systematic review that examined the relationship between protein intake and lean body mass sheds new light […]

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